Figure 2.
Effect of Na+ o on the membrane potential dependence of K 0.5 for Na,K -pump current activation with RD enzyme. K 0.5 values were obtained by fitting a Hill equation to data similar to those shown in Fig. 1 C and data taken from Argüello et al. 1996. The best-fit functions (solid curves) for K 0.5 vs. V M in the presence of 0 (•) and 148 (○) mM Na+ o were calculated with and , respectively. Fitting parameters are given in the text.