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. 2007 Nov 6;196(2):353–367. doi: 10.1677/JOE-07-0471

Figure 6.

Figure 6

Effects of IN3 on plasma membrane expression of HA-GnRHRs in MCF7 and LβT2 cells. LβT2 cells were cultured in plates that had been pretreated with Matrigel and MCF7 cells were either on Matrigel-treated plates (lower panel) or untreated plates (middle panel). The cells were infected with Ad expressing HA-tagged GnRHRs and then incubated for 16 h in medium with 0 (control) or 1·8×10−7 M IN3, as indicated, before imaging. The figure shows PCSE values pooled from seven separate experiments each with four replicates (mean±s.e.m., n=4–7). ANOVAs revealed IN3 as a significant variable (P<0·01) and the effects of IN3 were statistically significant (*P<0·05, **P<0·01 when compared with control values for matched cell and receptor type) for both receptors and both cell types.