Table 1.
Maternal weight before treatment, maternal weight gain during the last week of pregnancy (days 15–21), gestation length, litter size, male:female ratio and group, male, and female offspring weight at birth, postnatal day 21, and at 7 months of age (i.e. adulthood). Results are mean±s.e.m.
| Birth weight (g) | Postnatal weight Day 21 | Weight at 7 months | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Maternal weight before treatment (g) | Maternal weight gain (g) | Gestation length (d) | Litter size | Male:female ratio | Group | Male | Female | Group | Male (g) | Female | Group | Male (g) | Female | |
| VEH | 365±14 (n=8) | 97±5 | 22±0 | 13±2·0 | 1·1±0·1 | 6·6±0·1 (n=99) | 6·6±0·9 (n=55) | 6·5±0·8 (n=44) | 55·7±1·1 (n=52) | 56·4±1·7 (n=26) | 57·6±1·2 (n=26) | 525±13 (n=20) | 690±12 (n=10) | 360±15 (n=10) |
| DEX | 363±6 (n=9) | 58±5* | 22±0 | 12±1·8 | 1·2±0·2 | 5·7±0·1† (n=108) | 5·6±0·8† (n=56) | 5·7±0·7† (n=52) | 52·7±1·4 (n=56) | 54±2·1 (n=29) | 55·2±1·2 (n=52) | 507±19·5 (n=20) | 653±25 (n=10) | 353±13 (n=10) |
*P<0·05, †P<0·01 compared with vehicle group.