Table 4.
Multivariate analysis of viral factors associated with the development of hepatocellular carcinoma*
| OR (95% CI) | P value | |
|---|---|---|
| HBV genotype C | ||
| No | 1 | |
| Yes | 3.28 (0.89–12.13) | <0.10 |
| PC A1896 mutation | ||
| No | 1 | |
| Yes | 3.75 (1.14–12.34) | <0.05 |
| BCP T1762/A1764 mutation | ||
| No | 1 | |
| Yes | 11.14 (3.05–40.72) | <0.001 |
*
Analyses restricted to 126 subjects (HCC=90, chronic carriers=36) who had complete tests on HBV genotype (genotype C), PC and BCP genes. The multivariate model was adjusted for age, gender and race. BCP, basal core promoter; CI, confidence interval; HBV, hepatitis B virus; HCC, hepatocellular carcinoma; OR, odds ratio; PC, precore.