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vCXC-1-induced chemotaxis of human PBN. (A) Chemotaxis of neutrophils toward cell-free supernatants. IL-8 (12 nM) was added to mock-infected cell supernatants as a positive control (IL-8). (Bars = 2 SD.) (B) Induction of migration of PBN by recombinant vCXC-1(T23 form) compared with IL-8 and gro α. RANTES, a CC chemokine, is included as negative control. Chemotactic index represents the fold increase in migration over a basal level in the absence of chemokine.
