Figure 4.

Macrophages form peptide-specific conjugates with naive CD8+ T-cells. (A) Differential interphase contrast images of conjugates formed between differently loaded macrophages and CD8+ T-cells. Arrows indicate conjugated T-cells. (B) Number of conjugates formed between CD8+ T-cells and macrophages loaded with 1 μM BSA (□) or OVA (■) peptide or with differently opsonized beads. Results are presented as total T-cells per 100 macrophages and shown as arithmetic means ± SEM of five independent experiments; statistical comparison of BSA- and OVA-loaded macrophages was performed with the Mann-Whitney test (*p < 0.05).