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. 2000 Oct 1;116(4):535–546. doi: 10.1085/jgp.116.4.535

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© 2000 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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(A) Single-channel recordings of the MTSPA-modified K165C homodimer at −90 and −110 mV. Dotted lines represent zero-current level. Next to each trace are current amplitude histograms compiled from 30 s (top and bottom) of recording traces containing the 2-s examples on the left. (B) Single-channel recordings of the MTSPA-modified K165C-K165 heterodimer. Amplitude histograms were from 23 s (top) and 30 s (bottom) of recording traces. Capital and small letters represent the pores with big and small conductances, respectively. C, close; O, open. The smaller conductance level in the heterodimer corresponds to the MTSPA-modified pore and is equal to the conductance levels in the homodimer shown in A.