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Optimized model predictions for the effect of ZnCl2 on the g H-V relationship (shown in Fig. 7). is assumed for reasons described in the text, but with somewhat different parameters than in Fig. 11, where the τact effect is modeled: pK M is 8.0, pK a is 7.0, and a = 0.01. The model implies that the external Zn2+ receptor consists of three protonation sites, and that protonation of one site reduces the affinity of Zn2+ for the receptor 100-fold.
