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Collagen binding analyses of the DDR2-DS domain by SPR experiments. Overlay plots of the sensorgrams obtained for the interaction between 1.2–75 μM of the DDR2-DS domain and the immobilized collagen type II (A) and type IV (C). RU stands for resonance units. The plots based on the steady-state method in SPR for collagen type II and type IV are shown in (B) and (D), respectively. Error bars are standard deviations of three independent experiments.
