Table 2.
Age-dependent changes in HA content of papillas of 1- to 3-week-old Sprague-Dawley rats
| Level | 1 week old | 2 weeks old | 3 weeks old |
|---|---|---|---|
| 1. Tip | 0.313 ± 0.09a | 0.44 ± 0.02b | 0.563 ± 0.06c |
| 2. | 0.219 ± 0.02 | 0.41 ± 0.05 | 0.46 ± 0.018 |
| 3. | 0.157 ± 0.05 | 0.145 ± 0.05 | 0.21 ± 0.05 |
| 4. | 0.015 ± 0.007 | 0.145 ± 0.08 | 0.18 ± 0.026 |
| 5. Base | 0.018 ± 0.013 | 0.01 ± 0.007 | 0.078 ± 0.01 |
| 6. Control | 0.0 | 0.0 | 0.0 |
| Number of rats | 12 | 11 | 11 |
| Number of kidneys | 24 | 22 | 22 |
| Urine osmolarity | 311.9 ± 15.3d | 502 ± 43.5 e | 613.95 ± 29.9f |
| Number of rats | 27 | 71 | 10 |
| Range | 140–538 | 172–1731 | 205–1258 |
HA content was measured in μg HA (mg wet weight of slice)−1, and urine osmolarity in mosmol l−1. Values are means ±s.e.m.P values are: a vs. b = > 1 < 2%, b vs. c = < 0.01, d vs. e = < 0.01.