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A, extracellular application of 8-bromo-cAMP (500 μM, 3 min) reversibly increased the amplitude of kainate-induced currents. The enhancement showed similar latency and magnitude to the potentiation induced by 17β-oestradiol (n= 6). B, the recovery from enhancement induced by 8-bromo-cAMP (500 μM, 3 min) was significantly retarded when cells were intracellularly dialysed with E2-BSA (3.3 nM; n= 3).
