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. 1998 Feb 1;506(Pt 3):745–754. doi: 10.1111/j.1469-7793.1998.745bv.x

Figure 5. The decrease in recovery induced by intracellular E2-BSA was dose dependent.

Figure 5

The decrease in recovery was evident at 0.1 nM and was saturated at 0.1 μM. A Hill plot derived from the dose-response data gave an EC50 of 2.51 ± 3.18 nM and an nH of 0.39 ± 0.07. Prolongation of cAMP action is described as the percentage recovery at 15 min after removal of 8-bromo-cAMP. It should be noted that a persistent recovery (about 20 %) existed independent of E2-BSA concentration. n indicates the number of the cells tested.