Table 2.
Mean resting data and data at 
for twenty-nine female subjects divided into three groups based on the fall in Pa,O2 at
| Reduction in Pa,O2 (rest –) |
Group 1 (no EIAH; n = 7) | Group 2 (mild EIAH; n = 7) < 10 mmHg 10–20 mmHg | Group 3 (severe EIAH; n = 15) > 20 mmHg |
|---|---|---|---|
| Resting data | |||
| Height (cm) | 169 ± 3 | 162 ± 4 | 165 ± 7 |
| Weight (kg) | 65.5 ± 6.1* | 56.3 ± 2.8 | 56.9 ± 6.4 |
| DLCO (ml min−1 mmHg−1) | — | 25.3 ± 3.3 | 27.1 ± 5.1 |
| DLCO/VA (ml min−1 mmHg−1 l−1) | — | 6.63 ± 0.47 | 6.79 ± 0.71 |
| TLC (l) | 5.47 ± 0.33 | 5.26 ± 0.70 | 5.68 ± 0.08 |
| VC (l) | 4.18 ± 0.24 | 3.91 ± 0.61 | 4.07 ± 0.58 |
| MEF50 (l s−1) | 4.69 ± 0.20 | 4.18 ± 0.38 | 4.26 ± 0.47 |
| [Hb] (g dl−1) | 13.2 ± 1.4 | 14.2 ± 0.7 | 13.6 ± 0.6 |
| Data at
| |||
 (ml kg−1 min−1) |
47.4 ± 3.4* | 57.0 ± 3.1 | 60.6 ± 2.3 |
| (range) | 31–55 | 50–62 | 43–70 |
| (l min−1) | 3.10 ± 0.63 | 3.21 ± 0.51 | 3.45 ± 0.23 |
 (l min−1) |
103.9 ± 12.4 | 110.7 ± 10.5 | 107.0 ± 12.8 |
| VT (l) | 2.10 ± 0.29 | 2.12 ± 0.29 | 2.04 ± 0.41 |
| Frequency (breaths min−1) | 50 ± 7 | 53 ± 8 | 54 ± 9 |
/
|
29.8 ± 3.1 | 29.4 ± 3.5 | 27.7 ± 2.0 |
| VD/VT | 0.16 ± 0.03 | 0.15 ± 0.02 | 0.15 ± 0.01 |
| PA,O2 (mmHg) | 118.0 ± 3.2 | 119.3 ± 4.6 | 113.9 ± 2.9† |
| Pa,O2 (mmHg) | 93.3 ± 2.7* | 86.3 ± 0.5 | 73.2 ± 0.9† |
| A-aDO2 (mmHg) | 25.0 ± 2.3* | 33.5 ± 2.1 | 40.4 ± 2.3† |
| Sa,O2 (%) | 95.3 ± 0.4* | 93.8 ± 0.3 | 90.4 ± 0.2† |
| Pa,CO2 (mmHg) | 31.7 ± 1.2 | 32.1 ± 1.1 | 35.4 ± 0.7† |
| pH | 7.293 ± 0.047 | 7.268 ± 0.060 | 7.290 ± 0.065 |
| [Lactate] (mm) | 10.0 ± 1.5 | 10.5 ± 2.7 | 10.2 ± 1.7 |
| [K+] (mm) | 6.4 ± 0.3 | 6.3 ± 0.5 | 6.4 ± 0.7 |
| Body temperature (°C) | 38.3 ± 0.1 | 38.2 ± 0.1 | 38.2 ± 0.1 |
Values are means ± s.d.
*
significantly different from groups 2 and 3, P < 0.05
†
significantly different from groups 1 and 2, P < 0.05. , expiratory ventilation; VT, tidal volume; VD, dead space.