Table 1.
Parameters used to compute local SR Ca2+ fluxes associated with sparks
| Parameter | Value | Source |
|---|---|---|
| DyeT (nm) | 5 × 104 | Experimental value |
| KD (nm) | 740 | Escobar, Cifuentes & Vergara (1995) |
| kd,on (nm−1 ms−1) | 2.4 × 10−4 | Escobar, Cifuentes & Vergara (1995) |
| kd,off (ms−1) | 1.8 × 10−2 | Escobar, Cifuentes & Vergara (1995) |
| VSR (nm ms−1) | 2 × 103 | Tang & Othmer (1994) |
| KSR (nm) | 120 | Tang & Othmer (1994) |
| VSL (nm ms−1) | 19 | Tang & Othmer (1994) |
| KSL (nm) | 60 | Tang & Othmer (1994) |
| B0 (nm) | 2.15 × 105 | Hove-Madsen & Bers (1993) |
| kb,on (nm−1 ms−1) | 10−4 | Sipido & Wier (1991) |
| kb,off (ms−1) | 4 × 10−2 | Sipido & Wier (1991) |
| DCa-dye (μm2 ms−1) | 0.02 | Harkins, Kurebayashi & Baylor (1993) |
| DCa (μm2 ms−1) | 0.3 | Kushmeric & Podolsky (1969) |
| Δt (ms) | 2.1 | Temporal resolution of confocal microscope |
| Δr (μm) | 0.4 | Spatial resolution of confocal microscope |