Table 2.
Delays and rates of rises in [Ca2+]i after the stimulation of P2Y purinoceptors by 10 μm ATP in single guinea-pig hepatocytes
| External solution | Delay (%) | d[Ca2+]i/dt (%) |
|---|---|---|
| Na+ and Ca2+ | 56 ± 5 (7) | 78 ± 11 (5) |
| Na+ free | 51 ± 11 (4) | 69 ± 11 (3) |
| Ca2+ free | 94 ± 12 (5) | 88 ± 19 (3) |
Delays at −60 mV are expressed as a percentage of the delay at 0 mV on the same cell. Mean values represent pooled data from fluo-3- and furaptra-loaded cells. Rates of rise in [Ca2+]i (d[Ca2+]i/dt) measured with furaptra at −60 mV are expressed as a percentage of d[Ca2+]i/dt at 0 mV on the same cell. Results are expressed as the mean ± s.e.m. with the number of cells in parentheses.