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. 1998 Jun 1;509(Pt 2):599–606. doi: 10.1111/j.1469-7793.1998.599bn.x

Figure 1. Antioxidant activities in glomeruli, proximal tubules and TIS samples.

Figure 1

▪, glomeruli; Inline graphic, proximal tubules; □, TIS samples. t-SOD, manganese + copper/zinc superoxide dismutase; MnSOD, manganese superoxide dismutase. *P < 0.01vs. glomeruli; **P < 0.01vs. glomeruli and vs. proximal tubules.

Analysis of superoxide dismutases and catalase by Western blotting revealed higher enzyme protein levels in PT than in glomeruli (Fig. 2). Similarly, steady-state mRNA levels of these enzymes were significantly higher in PT than in glomeruli (Fig. 3). Among the different glutathione peroxidases, mRNA analysis was confined to cellular GSH-Px I. In contrast to results for SOD and catalase, GSH-Px mRNA levels in proximal tubules and glomeruli were the same.