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. 1998 Jun 1;509(Pt 2):471–485. doi: 10.1111/j.1469-7793.1998.471bn.x

Figure 3. Rapid recovery phase is abolished in Hepes buffer and absent during respiratory alkalosis.

Figure 3

All solutions Cl− free (replaced by gluconate). A, sample acetate prepulse in Hepes buffer. Note lack of recovery from alkali load; pHo 7.40. B, sample acetate prepulse in CO2/HCO3− buffer; pHo 7.40. Note the rapid partial pHi recovery. C, alkalosis induced by reducing PCO2 (as shown in bar above trace) from 10 to 5 % (gas mixture balanced with air); [HCO3−]o reduced simultaneously from 44 to 22 mM to maintain constant pHo. Note lack of pHi recovery from alkalosis.