Table 2.
Comparison of effects of testicular hyaluronidase and highly specific hyaluronidases (Streptomyces and leech) on synovial lining conductance dQs/dPj at low and high intra-articular pressures
| Below yield pressure | Above yield pressure | |||||
|---|---|---|---|---|---|---|
| Testicular hyaluronidase | Highly specific hyaluronidases | P | Testicular hyaluronidase | Highly specific hyaluronidases | P | |
| Absolute slopes* | 4.14 ± 1.06 (7) | 4.59 ± 0.54 (8) | 0.70† | 13.84 ± 1.69 (7) | 11.98 ± 1.37 (9) | 0.40† |
| Increase in slope** | 2.34 ± 1.16 (4) | 3.37 ± 0.52 (6) | 0.39† | 12.60 ± 2.19 (5) | 10.09 ± 1.55 (7) | 0.36† |
| Factorial increase*** | 5.36 ± 1.86 (4) | 5.69 ± 1.88 (6) | 0.76‡ | 6.68 ± 1.19 (5) | 5.16 ± 0.49 (7) | 0.34‡ |
Values are means ± s.e.m. in μl min−1 cmH2O−1. Values in parentheses, number of joints.
*
Value of slope dQ̇s/dPj after enzyme treatment.
**
Difference between control slope and slope after enzyme treatment in same animal.
***
Ratio of slope after enzyme treatment to control slope in same animal.
†
Unpaired t test
‡
non-parametric test on ratios, Mann-Whitney U test.