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Tabulation of affinity parameters for 5-[3H]HT uptake, 5-[3H]HT binding and [3H]imipramine binding measured in intact L-S1 cells
| 5-[3H]HT uptake | |
| 5-HT Km | 390 ± 45 nm |
| Imipramine Ki | 22.7 ± 3.4 nm |
| 5[3H]HT binding | |
| 5-HT Kd | 109 ± 9 nm |
| Imipramine Ki | 15.1 ± 1.3 nm |
| [3H]Imipramine binding | |
| 5-HT Ki | 800 ± 110 nm |
| Imipramine Kd | 6.0 ± 0.4 nm |
The 5-HT Km and the imipramine Ki values were reported previously (Frnka et al. 1991).
