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Effects of subretinal rAAV readministration on serum anti-rAAV NAb levels as measured by ELISA
| Day | Animal
|
|||
|---|---|---|---|---|
| 94B-102 | 95C-273 | 94B-051 | 94B-109 | |
| 0 First injection | 20 | 20 | 20 | 20 |
| 28 | 20 | 40 | 20 | 320 |
| 43 | 20 | 80 | 20 | 320 |
| 84 | 20 | 80 | 40 | 320 |
| 107 | 40 | 80 | 80 | 320 |
| 199 Second injection | − | 150 | ND | ND |
| 235 | − | 1,280 | 2,560 | ND |
| 285 | − | 1,280 | 2,560 | ND |
| 325 | − | 1,380 | 2,560 | ND |
Virus was readministered to the second eyes of animals 95C-273 and 94B-051 only on day 199. ND, not done.
