Table 3.
Effects of subretinal rAAV readministration on anterior chamber fluid anti-rAAV NAb levels as measured by ELISA
| Day | Animal
|
|||||||
|---|---|---|---|---|---|---|---|---|
| 94B-102 | 95C-273 | 94B-051 | 94B-109 | |||||
| Eye
| ||||||||
| 1 | Un | 1 | 2 | 1 | 2 | 1 | Un | |
| 0 | 20 | 20 | 20 | 20 | 20 | 20 | 20 | 20 |
| 43 | 20 | 20 | 20 | ND | 80 | 80 | 160 | 20 |
| 84 | 20 | 20 | 20 | 20 | 20 | 20 | 160 | 20 |
| 285 | − | − | 40 | 40 | 640 | 2,560 | ND | ND |
| 325 | − | − | 40 | 40 | 640 | 2,560 | ND | ND |
Eyes are designated 1 or 2 according to the scheme presented in Table 1. Eye 1 was injected at day 0. Eye 2 was injected at day 199. Only one eye was injected in animals 94B-102 and 94B-109. The second uninjected eyes of these animals are designated Un. ND, not done.