Table 3.
Changes in mean left atrial pressure (MLAP), mean arterial blood pressure (MABP), heart rate (HR), and peak intra-tracheal pressure (PITP) during graded increase in left atrial pressure (LAP) when RARs were investigated
| LAP (mmHg) | Initial control | +5 mmHg | +10 mmHg | Final control |
|---|---|---|---|---|
| Intact control + sham (n= 15) | ||||
| MLAP (mmHg) | 2.9 ± 0.8 | 8 ± 0.8 | 12.3 ± 0.8 | 2.1 ± 0.7 |
| MABP (mmHg) | 65.7 ± 3.7 | 53.9 ± 4.0 * | 45.2 ± 5.8 § | 62.1 ± 3.8 |
| HR (beats min−1) | 179.6 ± 6.9 | 180.3 ± 7.6 | 175.9 ± 12 | 173.5 ± 8.2 |
| PITP (mmHg) | 4.7 ± 0.2 | 5.3 ± 0.3 | 5.5 ± 0.3 * | 5.1 ± 0.3 |
| PVC 6 weeks (n= 10) | ||||
| MLAP (mmHg) | 5.6 ± 0.5 | 10.4 ± 0.7 | 16 ± 0.7 | 5.7 ± 0.7 |
| MABP (mmHg) | 55.4 ± 5.5 | 50.1 ± 5.5 | 39.2 ± 6.1 | 54.9 ± 5.9 |
| HR (beats min−1) | 164.5 ± 16.5 | 176.5 ± 14.1 | 176.3 ± 18.8 | 144.4 ± 18.8 |
| PITP (mmHg) | 7.7 ± 0.2 | 8.3 ± 0.2 | 8.8 ± 0.5 | 8.6 ± 0.4 |
| PVC 12 weeks (n= 10) | ||||
| MLAP (mmHg) | 6.6 ± 1.2 | 11.6 ± 1.1 | 16.6 ± 1.2 | 6.6 ± 1.2 |
| MABP (mmHg) | 64.6 ± 6.2 | 49.9 ± 7.1 | 43.8 ± 5.5 § | 59.7 ± 4.6 |
| HR (beats min−1) | 165.3 ± 11.8 | 170.5 ± 14.9 | 171.1 ± 18.5 | 155.9 ± 11.8 |
| PITP (mmHg) | 5.4 ± 0.7 | 5.7 ± 0.7 | 6.0 ± 0.7 | 5.5 ± 0.7 |
n,number of experimental runs.
*
Significantly different from initial control.
§
Significantly different from initial and final controls.