Figure 6. Time course of luminal pH and secretory rate during spontaneous secretion in the absence of Cl⁻.

Under the same experimental conditions as in Fig. 5, changes in luminal pH and fluid secretory rate were monitored for 20 min in the HCO₃⁻/ CO₂ bath solution before secretin (10 nM) was applied. A, changes in luminal pH; one of four experiments. B, changes in secretory rate; means ±s.e.m. of all four experiments.