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. 1998 Sep 15;511(Pt 3):915–933. doi: 10.1111/j.1469-7793.1998.915bg.x

Figure 1. Caffeine-induced contraction in α-toxin-permeabilized tracheal SM.

Figure 1

The 30 mM caffeine response without GTP was repeated four times in the same strip (A). The caffeine response was compared in the presence or absence of GTP in the same strip (B). The dose-response relationship for caffeine was determined in seven strips. The peak amplitude was normalized to the maximum contraction at pCa 5.0, and expressed as the mean ±s.e.m. (C). After the 30 mM caffeine response and its washing out for 3 min, 100 μm carbachol (CCh) was added to the strip in the presence of 50 μm GTP (D). The traces in A, B and D represent at least four separate experiments.