Figure 8. Effect of Cd2+ on Ito in human myocytes.
ICa,L was blocked by nisoldipine (10 μm). Steady-state activation and inactivation curves of Ito in the absence and presence of Cd2+. Inset, voltage dependence of the Ito inactivation time constant in the absence and presence of Cd2+. □, control; •, 0.3 mM Cd2+; ▵, second control.