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. 1998 Oct 1;512(Pt 1):137–148. doi: 10.1111/j.1469-7793.1998.137bf.x

Figure 1. pHichanges after switching the extracellular solution from Hepes-buffered solution to HCO3-buffered solution.

Figure 1

A, continuous recording of pHi from a rat cardiac myocyte loaded with SNARF-1 AM before and after changing the superfusate from a Hepes-buffered solution to a HCO3-buffered one. B, mean pHi data recorded from 7 myocytes subjected to the experimental protocol shown in A. The change from Hepes-buffered to CO2/HCO3-buffered superfusate (at constant pHo) induced a transient acidification due to CO2 permeation that was followed by a recovery to values similar to control.