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Comparison of the effects of 10 mm spermine application during a 100 μm NMDA-evoked steady-state current in the presence of 10 or 100 μm Ro8-4304
| Potentiation | Relaxation | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| τ1 (ms) | Amplitude (%) | τ2 (ms) | Amplitude (%) | Maximum (% control) | τ1 (ms) | Amplitude (%) | τ2 (ms) | Amplitude (%) | |
| 10 μm Ro 8-4304 | 100 ± 15 | 30 ± 3 | 984 ± 92 | 70 ± 3 | 800 ± 77 | 84 ± 6 | 77 ± 8 | 464 ± 92 | 23 ± 9 |
| 100 μm Ro8-4304 | 79 ± 5 | — | — | — | 359 ± 24 | 43 ± 4 | — | — | — |
