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. 1999 Aug 17;96(17):9926–9931. doi: 10.1073/pnas.96.17.9926

Figure 3.

Figure 3

Effect of internal MTSEA and MTSET on amino-terminal cysteine mutant channels. Bars represent steady-state inhibition of current at −80 mV by 2.5 mM MTSEA or 2 mM MTSET applied to the intracellular side. The responses of wild-type and IRK1J channels are shown for comparison. Current was elicited by voltage ramps from −100 mV to +80 mV over 70 ms from a holding potential of −40 mV. Black bars indicate responses that are significantly different from the response of IRK1J channels (P < 0.05). Error bars represent SD (n = 3–6). Mutant channels rescued by tandem tetramers are marked with an asterisk.