Table 1.

Major cardiac parameters for the WKY and SHR groups

	WKY						SHR
	All ages n = 8		8 week n = 4		12 week n = 4		All ages n = 8		8 week n = 4		12 week n = 4
	Mean	s.e.m.	Mean	s.e.m.	Mean	s.e.m.	Mean	s.e.m.	Mean	s.e.m.	Mean	s.e.m.
Body weight (BW) (g)	249	15	214	9	284	13	277	14	246	9	307	13
LV myocardial volume by MRI (LVMV) (μl)	476	26	429	30	523	28	646*	22	608	6	684	35
LVMV/BW (μl g−1)	1.92	0.05	2.00	0.07	1.84	0.04	2.36*	0.09	2.48	0.10	2.24	0.09
End-diastolic volume (μl)	397	31	331	21	463	36	414	20	374	22	455	19
End-systolic volume (μl)	157	18	119	13	195	20	210†	8	196	9	224	9
Ejection fraction	0.61	0.02	0.64	0.03	0.58	0.01	0.49*	0.02	0.47	0.04	0.51	0.01
Systolic blood pressure (mmHg)	150	2	151	4	150	2	200*	11	177	10	216	7

Data are presented for the combined age groups of each strain, as well as for each age group separately. The left ventricular (LV) myocardial volume measured by MRI, for each individual rat, was taken from the average value from all the time points sampled in the cardiac cycle. The functional cardiac parameters were established from the transverse cardiac sections. Values quoted are the means and the standard error of the mean (s.e.m.).

^*P < 0.001versus control WKY for both age groups combined.

^†P < 0.05versus control WKYfor both age groups combined.