Figure 7. oIPSC reversal potential is unaffected when depressed by dopamine, in accordance with a presynaptic site of dopamine action.

A, IPSCs from a single cell recorded at membrane potentials in the range −60 to −100 mV under control conditions (left), and in dopamine (30 μM; right), which depresses the IPSCs in a voltage-independent manner. B, plot of pooled data from 3 experiments such as that in A, with IPSC amplitude in each experiment normalized to that seen under control conditions at −60 mV. The IPSC amplitude in dopamine (□) was reduced in a voltage-independent manner relative to control (▪), but with its reversal potential (of −78 mV) essentially unchanged from that in control (−80 mV).