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. 2000 Dec 1;116(6):769–780. doi: 10.1085/jgp.116.6.769

Table 1.

Summary of Effects of Agonists and Inhibitors on Different Channel Types

cGMP cAMP DAG Tetracaine
Channel K1/2 K1/2 Efficacy IC50 Maximal percentinhibition IC50 Percentinhibition
Brod 31.0 1830 0.05 0.83 100 2.6 94.1
Rolf 2.1 37 1 3.24 31 139.6 10.4
Molf 1.2 37 1 3.50 17 18.8
Molf G204E 1.9 37 1 0.99 100 10.8 78.3
Rolf G204E 1.8 37 1 0.73 100 76.4
Rolf G204W 14.0 440 0.44 0.26 100 2.2 100