Table 2.
Antiproliferative activity against mutant P388 leukemia cells
| Drug | Cell line
|
||
|---|---|---|---|
| P388 | Etopor-P388 | Camptor-P388 | |
| Ecteinascidin 743 | 0.22 | 0.24 | 0.30 |
| Pt650 | 0.19 | 0.18 | 0.21 |
| Camptothecin | 53 | 42 | 3.5 × 104 |
| Etoposide | 96 | 2.5 × 103 | 3.4 × 102 |
| Vincristine | 1.9 | 2.1 | 3.3 |
Values reported are IC50 in nM.