Table 2.
Equilibrium Parameters for Activation and Inactivation
Activationparameter | Range definedin Cox et al. | Values from fit toG-V curves | |
---|---|---|---|
L(0) | 1,647–2,029 | 1,775 ± 1,280 | |
Q | 1.35–1.40e | 1.26 ± 0.13e | |
KC | 8.68–11.0 | 10.11 ± 0.75 | |
KO | 1.04–1.1 | 0.66 ± 0.005 | |
Equilibrium inactivation parameters | Values used for simulating currents | Values obtained from fit to G-V curves | Values obtained from |
fit to instantaneous I-V | |||
Blocking parameters: Kx(V) = Kx(0) · exp(QxFV/RT) | Kx(0)Qx | Kx(0)Qx | Kx(0)Qx |
K1(V) | 1.20.433e | 0.31 ± 0.10.44e ± 0.014 | |
K2(V) | 1.120.225e | 2.17 ± 3.60.19e ± 0.2 | 2.27 ± 0.045 0.21e ± 0.005 |