Figure 2.

PTK inhibitors reduce the genistein inhibition. (A) Inhibition of closed rod photoreceptor CNG channels by 1 min pre-exposure to 100 μM genistein alone or together with PTK inhibitors (500 μM AMP-PNP or 100 μM erbstatin). Closed channels were activated by application of 2 mM cGMP (control). (B) Inhibition of fully activated channels by genistein alone or together with PTK inhibitors.