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. Author manuscript; available in PMC: 2008 Feb 6.
Published in final edited form as: Pharmacol Rev. 2006 Mar;58(1):87–114. doi: 10.1124/pr.58.1.6

Fig. 5.

Fig. 5

XOR is up-regulated in patients with heart failure. A, representative Western blot of myocardial extracts from patients with end-stage idiopathic dilated cardiomyopathy (CM) and patients with normal cardiac function (NL) probed with monoclonal anti-XDH antibody. Bands corresponding to both XDH (145 kDa) and XO (125 and 85 kDa). B, densitometry depicting the average XDH/XO signal from all patients. The total XDH/XO signal is increased by 60% in idiopathic dilated cardiomyopathy. *, P < 0.05 by Student’s unpaired t test. Reprinted from Cappola et al. (2001), with permission from Lippincott Williams & Wilkins (Philadelphia, PA).