Table 1.
Conductances of Xenopus Oocytes Expressing CFTR
Unstimulated | cAMP-stimulated | |||
---|---|---|---|---|
24 h | 48 h | 72 h | ||
Mock | 2.9 ± 1.7 (11) | 2.7 ± 1.4 (4) | 2.9 ± 1.6 (4) | 3.2 ± 2.1 (3) |
hCFTR | 4.2 ± 3.8 (35) | 426 ± 60 (16) | 685 ± 131 (13) | 1,147 ± 217 (6) |
XCFTR | 3.1 ± 2.1 (34) | 214 ± 50 (14) | 1,009 ± 268 (14) | 2,028 ± 217 (6) |
Xenopus laevis oocytes were injected with water (mock), hCFTR cRNA, or XCFTR cRNA, and their membrane conductances were measured at 24, 48, or 72 h after injection with and without stimulation with cAMP cocktail. Conductances are expressed in microSiemens. Each result represents the mean ± SEM of n experiments (numbers in parentheses).