Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2001 Oct 1;118(4):433–446. doi: 10.1085/jgp.118.4.433

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2001 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

I-V relationship of R334C CFTR is modified by MTSET⁺ and MTSES⁻. (A) I-V plots at steady-state activation. Oocytes were continuously perfused with a cocktail containing 10 μM isoproterenol and 1 mM IBMX (control). An ∼5-min exposure to 1 mM MTSET⁺ induced an approximate doubling of the conductance and a change in the shape of the I-V plot. (B) I-V plots obtained at steady-state activation (control) and after ∼5-min exposure to 1 mM MTSES⁻ that attenuated the conductance by ∼50% and enhanced inward rectification.