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. 2003 Oct;122(4):459–469. doi: 10.1085/jgp.200308818

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Copyright © 2003, The Rockefeller University Press

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Figure 9. — Time course of MTSET modification. Currents were measured at the end of the test pulse. Monoexponential fits are superimposed (red lines). (A) Time course of MTSET modification of the G163C mutant. (B) Time course of MTSET modification of the R165C mutant. (C) Time course of MTSET modification of the R174C mutant. (D) Time course of MTSET modification of the R176C mutant. (E) Time course of MTSET modification of the R177C mutant. Notice that in this case only closed channels are modified by MTSET. (F) Time course of MTSET modification of the S179C mutant. Only closed channels are modified by MTSET. (G) Mutant L181C was insensitive to the MTSET treatment in both closed and open/closed states.