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. 2003 Oct;122(4):459–469. doi: 10.1085/jgp.200308818

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Copyright © 2003, The Rockefeller University Press

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Figure 4. — Properties of KAT1 gating currents. (A) Gating charge calculated as the time integral of the ON gating currents shown in Fig. 3 B. (B) Gating charge calculated as the time integral of the OFF gating currents shown in Fig. 3 B. Between −80 and −120 mV the gating charge time course is well described by a single exponential fit with a time constant of the order of 300 μs. Between −140 and −180 mV, a biexponential fit is necessary to account for the gating charge time course. (C) Comparison between normalized Q _ON and Q _OFF. Data was fitted using Eq. 2 with: z_{g − ON} = 0.56 ± 0.10, V_{1/2 − QON} = −176 ± 9 mV; z_{g − OFF} = 0.57 ± 0.15, V_{1/2 − QOFF} = −172 ± 10 mV (n = 5).