Figure 13.
W434F channels are slow to enter the C-inactivated state. Traces were recorded in symmetrical 115 Na+ solutions from an inside-out patch containing W434F channels. The standard double pulse protocol was used with (A) a 15-ms and (B) a 10-s first pulse duration. Despite the dramatic increase in the duration of the first pulse, little slowing in charge recovery is seen (15 ms first pulse: 83%, 10 s first pulse: 71%). The interpulse duration was 15 ms. The large Na+ tail currents were omitted from the figure for clarity.
