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. 2001 Aug 1;118(2):145–156. doi: 10.1085/jgp.118.2.145

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© 2001 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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The maximum fusion rate and the time to reach the maximum rate (T_Peak) vary with calcium. Using the relationship between the extent of fusion (pCa and n), the experimentally derived constants for α, and the correlation between n and p, specifies the kinetic response as a function of calcium. The solid lines indicate these relationships, in agreement with the observed behavior of both the maximum rate and the time to reach the maximum rate.