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. 2001 Aug 1;118(2):193–206. doi: 10.1085/jgp.118.2.193

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© 2001 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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Residue-specific environmental parameter profiles obtained for the second transmembrane domain TM2: mobility parameter ΔH_o ⁻¹ (top, closed circles); oxygen accessibility parameter ΠO₂ (middle, open squares); and NiEdda accessibility parameter ΠNiEdda (bottom, closed circles). The dotted line in the top panel represents the average ΔH_o ⁻¹ value for the entire segment. Arrows point to those residues with in-phase accessibility and/or probe mobility peaks.