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. 2002 Jun;119(6):571–580. doi: 10.1085/jgp.20018544

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Copyright © 2002, The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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Figure 1. — Rundown of whole-cell currents in COS_WT (A–C) and COS_phox (D–F) cells. Families of currents were recorded at various times after establishing whole cell configuration at pH_i 5.5 and pH_o 7.0 in TMAMeSO₃ solutions. Insets illustrate the voltage pulses, which were applied at an interval of 15 s. Results are representative of 6 COS_WT cells and 22 COS_phox cells. The current at the holding potential decreased progressively during most of the families of pulses illustrated.