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. 2004 Sep;124(3):239–258. doi: 10.1085/jgp.200409071

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Copyright © 2004, The Rockefeller University Press

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Figure 8. — Release permeability changes with SR depletion. (A) Test release flux ≲t following depleting pulses of various durations, as indicated. (B) Peak (circles) or steady value of level of ≲t , vs. Ca_SR normalized to its resting value. While the peak release flux is roughly proportional to Ca_SR, the steady value is nearly constant, indicating increase in steady permeability. (C) Corresponding _c t , corrected according to Eq. 13 (“first approximation”). (D) Peak or steady values of _c t , corrected according to Eq. 13 (filled) or Eq. A5 (open symbols). Both corrections yield qualitatively similar dependences. Identifier 1726.

Inline graphic — Release permeability changes with SR depletion. (A) Test release flux ≲t following depleting pulses of various durations, as indicated. (B) Peak (circles) or steady value of level of ≲t , vs. Ca_SR normalized to its resting value. While the peak release flux is roughly proportional to Ca_SR, the steady value is nearly constant, indicating increase in steady permeability. (C) Corresponding _c t , corrected according to Eq. 13 (“first approximation”). (D) Peak or steady values of _c t , corrected according to Eq. 13 (filled) or Eq. A5 (open symbols). Both corrections yield qualitatively similar dependences. Identifier 1726.