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. 2005 Jun;125(6):535–553. doi: 10.1085/jgp.200409216

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Copyright © 2005, The Rockefeller University Press

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Figure 10. — Ca²⁺ signaling and contraction induced by caffeine in airway SMCs. (A) Repetitive contractile responses of an airway to sequential stimulation with 20 mM caffeine as indicated by top bars. (B, C, D, and E) Simultaneous recordings of changes in [Ca²⁺]_i in single SMCs and contraction of the airway lumen during the stimulation with 20 mM caffeine in the presence or absence of extracellular Ca²⁺ or 1 mM NiCl₂ as indicated by top bars. Representative traces of at least four experiments from different slices of two mice.