TABLE I.
Modulation of the dSlo Conductance–Voltage Relationship by Slob71, 65, 53, and 47
| Transfection condition | V1/2 ± SEM (mV) | Slope ± SEM |
|---|---|---|
| dSlo + Vector (n = 15) | 16.2 ± 0.7 | 21.9 ± 0.6 |
| dSlo + Slob71 (n = 13) | 7.3 ± 0.7a | 24.1 ± 0.6 |
| dSlo + Slob 65 (n = 14) | 8.8 ± 0.6a | 22.2 ± 0.6 |
| dSlo + Slob53 (n = 15) | 8.8 ± 0.7a | 26.1 ± 0.6 |
| dSlo + Slob47 (n = 10) | 8.6 ± 0.9a | 24.7 ± 0.8 |
The V1/2 for dSlo activation and the slope of the conductance–voltage relationships were obtained from the curves shown in Fig. 4.
a
Significantly different from dSlo + Vector (P < 0.001; Student's t test).