Table 2.
S-exons | C-exons | MW | Internal exons | |
Set size | ||||
Mutated donor sites | 67 | 42 | ||
Mutated acceptor sites | 42 | 72 | ||
All | 109 | 114 | 154846 | |
Exon length (nucleotides) | ||||
Mutated donor sites | 114 | 147 | 0,024 | |
Mutated acceptor sites | 112,5 | 130 | n/s | |
All | 114 | 136 | 0,020 | 123 |
Densities of cis-acting elements(candidate sites per nucleotide) | ||||
ESEfinder: SC35 | ||||
Mutated donor sites | 0,043 | 0,042 | n/s | |
Mutated acceptor sites | 0,038 | 0,045 | n/s | |
All | 0,042 | 0,043 | n/s | 0,038 |
ESEfinder: SF2/ASF | ||||
Mutated donor sites | 0,025 | 0,037 | 0,048 | |
Mutated acceptor sites | 0,036 | 0,041 | n/s | |
All | 0,028 | 0,040 | 0,005 | 0,036 |
ESEfinder: SRp40 | ||||
Mutated donor sites | 0,034 | 0,043 | 0,006 | |
Mutated acceptor sites | 0,040 | 0,043 | n/s | |
All | 0,035 | 0,043 | 0,004 | 0,040 |
ESEfinder: SRp55 | ||||
Mutated donor sites | 0,028 | 0,024 | n/s | |
Mutated acceptor sites | 0,022 | 0,023 | n/s | |
All | 0,025 | 0,023 | n/s | 0,023 |
RESCUE-ESE | ||||
Mutated donor sites | 0,090 | 0,108 | n/s | |
Mutated acceptor sites | 0,100 | 0,080 | n/s | |
All | 0,091 | 0,094 | n/s | 0,099 |
PESE | ||||
Mutated donor sites | 0,048 | 0,082 | 0,007 | |
Mutated acceptor sites | 0,057 | 0,055 | n/s | |
All | 0,055 | 0,064 | 0,023 | 0,064 |
PESS | ||||
Mutated donor sites | 0,012 | 0,008 | n/s | |
Mutated acceptor sites | 0,009 | 0,007 | n/s | |
All | 0,011 | 0,007 | n/s | 0,007 |
Splice site scores | ||||
Mutated donor sites | ||||
Authentic donor sites | 18,52 | 18,49 | n/s | 18,82 |
Acceptor sites of the (upstream) exon | 18,70 | 19,67 | n/s | 19,08 |
Acceptor sites of the (downstream) intron | 19,37 | 18,98 | n/s | 19,09 |
Mutated acceptor sites | ||||
Authentic acceptor sites | 19,59 | 18,72 | 0,05 | 19,08 |
Donor sites of the (downstream) exon | 18,44 | 18,56 | n/s | 18,82 |
Donor sites of the (upstream) intron | 18,48 | 18,51 | n/s | 18,79 |
Distance to the closest candidate site(nucleotides) | ||||
Mutated donor sites | 220,5 | 75 | 0,067 | 289 |
Mutated acceptor sites | 185 | 66 | 0,024 | 81 |