Table 2.
Genes regulated similarly in PR versus P and P versus V.
| Gene symbol | Probe ID a | FC b | Gene description | Biological process c | |
|---|---|---|---|---|---|
| PR versus P | P versus V | ||||
| Akp2 | 1423611_at | −11.5 | −2.0 | Alkaline phosphatase | Marker of osteoblasts |
|
| |||||
| Cd2bp2 | 1417224_a_at | −1.9 | −1.5 | CD2 antigen binding protein 2 | T cell activation |
|
| |||||
| Cd29 (Itgb1) | 1426918_at | −2.1 | −1.5 | Integrin beta 1 (fibronectin receptor beta) | Regulation of progression through cell cycle, G1/S transition of mitotic cell cycle, cell adhesion, cell-matrix adhesion, integrin-mediated signaling pathway, development, positive regulation of cell proliferation, negative regulation of cell differentiation |
|
| |||||
| Cd44 | 1423760_at | −3.9 | −5.6 | CD44 antigen | Cell surface glycoprotein, cell adhesion, stem cells, implicated in tumor growth and dissemination |
|
| |||||
| Cd105 (Eng) | 1432176_a_at | −2.3 | −2.0 | Endoglin | Angiogenesis, cell adhesion, heart development, regulation of transforming growth factor beta receptor signaling pathway |
|
| |||||
| Cd109 | 1425658_at | −2.8 | −5.2 | CD109 antigen | Membrane glycoprotein, elevated expression in variety of cancers |
|
| |||||
| H2-D1 | 1451934_at | −3.2 | −3.0 | Histocompatibility 2, D region locus 1 | Immune response, detected on surface of MSC and adipocyte stem cells at low levels and reduced with passage |
|
| |||||
| H2-K1 | 1427746_x_at | −1.6 | −1.5 | Histocompatibility 2, K1, K region | Immune response, antigen presentation |
|
| |||||
| Mki67 | 1426817_at | −4.3 | −5.9 | Antigen identified by monoclonal antibody Ki 67 | Meiosis, cell proliferation |
|
| |||||
| Pcna | 1417947_at | −2.4 | −1.7 | Proliferating cell nuclear antigen | DNA replication |
|
| |||||
| S100b | 1434342_at | −4.2 | −2.7 | S100 protein, beta polypeptide, neural | Marker of differentiated neural cells |
|
| |||||
| Spred1 | 1460116_s_at | −1.9 | −2.1 | Sprouty protein with EVH-1 domain 1, related sequence | Inhibition of MAP kinases, activated in hematopoietic cells, involved in mesoderm organization, inhibit Ras pathway (G protein) |
|
| |||||
| Spred2 | 1434403_at | −2.3 | −1.7 | Sprouty protein with EVH-1 domain 2, related sequence | As above |
|
| |||||
| Stag1 | 1434189_at | −1.5 | −1.7 | Stromal antigen 1 | Key mediator of p53-dependent apoptotic pathway, cell cycle, chromosome segregation, mitosis, and cell division |
|
| |||||
| Stag2 | 1421849_at | −1.6 | −1.6 | Stromal antigen 2 | As above |
|
| |||||
| Cd1d1 | 1449130_at | 4.9 | 5.1 | CD1d1 antigen | MHC class I-like glycoprotein, development and function of natural killer T lymphocytes |
|
| |||||
| Cd151 | 1451232_at | 1.9 | 1.5 | CD151 antigen | PPAR positively regulates it in squamous cell carcinoma, implicated in tumor invasiveness |
|
| |||||
| Fabp4 | 1424155_at | 69.6 | 1.7 | Fatty acid binding protein 4 | Marker of differentiated adipocytes |