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. 2008 Jan 25;105(5):1478–1482. doi: 10.1073/pnas.0710366105

Fig. 2.

Fig. 2.

Structures of the CTX reagents and the mechanism by which the cleavable linker is severed by reductant. (a) Cysteine-modifying charybdotoxins. (b) Tris(2-carboxyethyl)phosphine (TCEP) cleavage of bis(N-phenylcarbamoyl)disulfane linkers and the resultant products.