1. Preventing the deployment of aberrant protein conformers |
2. Retaining precursor proteins in an environment suitable for their maturation |
3. Favoring correct assembly by increasing subunit concentration |
4. Reducing the risks of proteotoxicity by inhibiting aggregation and degrading terminally misfolded proteins |
5. Maintaining homeostasis in the early secretory pathway |
6. Developmental regulation of protein secretion (IgM, adiponectin) |
7. Storing proteins for regulated secretion (plants, adipocytes) |
QC, quality control. |